EGFR and non-small cell lung carcinoma: However, a novel radiotracer, 18F-N-(3-chloro-4-fluorophenyl)-7-(2(2-(2-(2-(4-fluorine)ethoxy)ethoxy)-ethoxy)-6-(3-morpholinopropoxy)quinazoline-4-amine (18F-IRS) based on gefitinib has been designed and synthesized, with 18F-IRS PET/CT showing potential to diagnose NSCLC EGFR mutation according to higher 18F-IRS uptake in NSCLC with EGFR mutations (69).