found that BRD1 inhibition could attenuate the function of sulfatide to reduce H3K9/14 acetylation and repress the occupancy of histone acetyltransferase binding to ORC1 (HBO1) and monocytic leukemia zinc finger (MOZ) in the promoter of the integrin αV gene in liver cancer cells, reducing migration and invasion (76). The gene discussed is ORC1; the disease is liver cancer.