As the authors expected, the CAR-T cells target the human chondroitin sulfate proteoglycan 4 (CSPG4) and aPDL1 antibodies binding to the tumor cells and blocking PDL1, and the combined CAR-T-P-aPDL1@gel system efficiently prevented the tumor recurrence after surgery in mice (78). The gene discussed is CSPG4; the disease is neoplasm.