Moreover, high MDH scores in ICGC-LIHC samples were markedly positively correlated with high CD8 T cell and B cell levels and negatively correlated with eosinophil cell levels in HCC (Figure S7A), and high MDH scores caused comprehensive elevated expression of MHC molecules, costimulatory molecules, and adhesion molecules in HCC (Figure S7B). The gene discussed is CD8A; the disease is hepatocellular carcinoma.