After using miR-183 analogues to treat rats with I/R injury, they found that the expression of pro-inflammatory proteins (IL-1β, IL-6 and TNF-α), the neurological function score of rats and the volume percentage of cerebral infarction decreased, the activity of microglia increased, and the expression of NF-κB p65 and I-κBα decreased and increased, respectively. Here, NFKB1 is linked to cerebral infarction.