IFNG and cancer: Thorsson et al (28) defined six immune subtypes across 33 cancer types, and our results showed that most PCa patients belong to the inflammatory subtypes, and 13.2% of high-risk and 4.0% of low-risk patients belong to the wound healing subtype, and 5.4% of high-risk and 3.0% of low-risk patients belong to IFN-γ dominant subtype (P < 0.01), and patients with high-risk + C1/C2 exhibited poorer RFS (Figures 6J–L).