ITGAM and acute respiratory distress syndrome: More specifically, results support the hypothesis that LPS-induced DEspR+CD11b+ neutrophils contribute to the disruption of blood-tissue barriers, and provide experimental support for the strong correlation (Rs > 0.7) of DEspR+ “rogue” neutrophil-subset with SOFA-score in ARDS (23) and with 90-day modified Rankin Scale score for outcome in sICH patients (34).