The consistent detection of the DEspR+ neutrophil-subset across three species in different LPS-induced neutrophilic inflammation models with increasing severity – 1) segmental neutrophilic inflammation and pulmonary-vascular barrier disruption model in human volunteers (33), 2) transient hypoxemia/ALI in macaques, and 3) high-mortality encephalopathy in rats – independently corroborate the neutrophil-subset with surface immunotype DEspR+CD11b+/CD66b+. The gene discussed is CEACAM8; the disease is Encephalopathy.