For instance, CAR-T cells targeting the Mullerian inhibiting substance type 2 receptor (MISIIR), B7-H3, Epithelial cell adhesion molecule (EpCAM), C-X-C chemokine receptor 1 (CXCR1), or C-X-C chemokine receptor 2 (CXCR2), 5T4 significantly controlled tumor growth in vivo (55–59). Here, EPCAM is linked to neoplasm.