Furthermore, single-cell analysis reveals that, in breast cancer, myCAF can be divided into five different clusters (ecm-myCAF, TGFβ-myCAF, wound-myCAF, IFNαβ-myCAF, and acto-myCAF), and ecm/TGFβ-myCAF clusters are related to the resistance to immunotherapy (13). This evidence concerns the gene TGFB1 and breast carcinoma.