Zhang et al. (2017) further confirmed that IL-17A inhibits hepatocyte autophagy through the IL-10/STAT3 signaling pathway and plays a pivotal role in the pathogenesis of LF. Moreover, natural killer, natural killer T, memory B, and central memory CD4 T cells have been demonstrated to be involved in the occurrence and development of LF (Wang and Yin, 2015; Huang et al., 2020; Zuluaga et al., 2020; Zuluaga et al., 2022). This evidence concerns the gene IL17A and Lassa fever.