- potent and selective inhibitor of CK2 (IC50 of 7 nM) and minor effects on CK1δ and CK1α activities- inhibition of PIM2 (IC50 of 13 nM)- inhibition of the phosphorylation of clock proteins, including PER2- cell type-dependent inhibition of cancer cell growth that correlated with cellular clock function- in vitro potency and selectivity comparable to CX4945. Here, PIM2 is linked to cancer.