A similar targeting profile was observed for hsa-miR-192-5p: the canonical form bound EMT master-regulator ZEB2 (Dongre & Weinberg, 2019) and angiogenesis stimulator WNK1 (Sie et al., 2020), while non-canonical 5′-isomiR regulated two other colorectal cancer oncogenes: NOX4 (Lin et al., 2017) and MSN (Kim et al., 2012). This evidence concerns the gene NOX4 and colorectal cancer.