Excessive visceral fat distribution is accompanied by several alterations in hormonal, inflammatory and endothelial levels, and these alterations induce stimulation of several other mechanisms through increased insulin resistance, RAAS and sympathetic nervous system stimulation, impaired stress and chemoreflex cardiovascular control, endothelial dysfunction and increased sodium retention, leading to an increase in blood pressure levels [9]. This evidence concerns the gene INS and endothelial dysfunction.