CYP2R1 and type 1 diabetes mellitus: The results show that carrying the CYP2R1 (rs1993116) allele C in conjunction with the CYP2R1 (rs12794714) genotype CC or allele T increases the risk of T1D, the ORs (and 95% CI) were 2.342(1.218–4.504), 1.956(1.014–3.771), respectively (Table 5).