RAB5A and infection: Collectively, this experiment did affirm the ability of MDMs to express Rab5 and Rab7 upon infection with mycobacteria, revealing higher levels for JD+ cows, suggesting re-exposure to MAP antigen elicited a trained or memory-like response resulting in heightened activation of the MDM (Kleinnijenhuis et al., 2012; Netea et al., 2016).