NUP214 and acute myeloid leukemia: DEK was initially discovered as a fusion protein with a nucleoporin (DEK-CAN, a.k.a.: DEK-NUP214) in a subset of acute myeloid leukemia (AML) patients, and indeed, DEK does play a role in disorders of white blood cell function, including autoimmune disorders and malignancies like AML (Garcon et al., 2005).