MAPT and frontotemporal dementia: FTD-tau is deemed as a diagnostic basis to several neuropathological conditions according to the morphology of the major tau isoforms and the inclusion bodies in such aggregates Thus, FTD-tau includes Pick's disease (PiD) characterized by 3R tau pathology, 4R tau lesions PSP, corticobasal degeneration (CBD), and globular glial tauopathy (GGT).