SPRY4 and breast cancer: The results of ROC curve analysis illustrated that the blood levels of SPRY4‐IT1, XIST, and H19 lncRNAs have excellent potential in discriminating breast cancer from the healthy controls, showing an AUC of 1.0 (95% CI 1.0–1.0, p = .00), 0.898 (95% CI 0.815–0.981, p = .00), and 0.848 (95% CI 0.701–0.995, p = .01), respectively (Figure 4).