In the fertile group, the expression of the INSR gene was2.61 times higher (P=0.002, 95% CI: 0.639-2.622) andthe IRS-1 gene was 2.87 times higher (P=0.008, 95% CI:0.177-1.137) than the infertile group. The gene discussed is IRS1; the disease is Infertility.