LP17 also alleviates zebrafish dyskinesia and downregulates TREM-1, iNOS, and calpain-1 mitochondrial RNA (mRNA) expression in 6-hydroxydopamine (6-OHDA)-induced zebrafish PD models while also reversing the downregulation of tyrosine hydroxylase (TH) protein expression and the upregulation of TNF-α protein expression induced by 6-OHDA. The gene discussed is TH; the disease is Parkinson disease.