The univariate analysis was conducted on the available data, showing that male, age, BMI, ALT, GGT, AST, GLB, TB, Scr, SUA, TC, BUN, TG, LDL-C and TG/HDL-C ratio were positively linked to Pre-DM, while ALB, DBIL and HDL-C were negatively associated with Pre-DM (Additional file 1: Table S1). This evidence concerns the gene GPT and diabetes mellitus.