In subgroup analysis, TG/HDL-C ratio was associated with pre-DM at different ages, sexes, BMI and ALT, but stronger in female and the population with 30 years  < age  < 40 years, 18.5 kg/m2 ≤ BMI < 24 kg/m2, and ALT ≤ 40U/L. This evidence concerns the gene GPT and diabetes mellitus.