Furthermore, the Kaplan–Meier analysis indicated a statistically significant inverse correlation between G6PD levels and overall survival (OS) in MM patients from the clinical datasets of both the University of Arkansas Total Therapy 2 (TT2) and the Dutch-Belgian cooperative trial group for hematology oncology group-65 (HOVON65) cohorts (Fig. 1g, h). The gene discussed is G6PD; the disease is Miyoshi myopathy.