The risk of maternal hypoglycaemia (RR 0.80, 95% CI 0.61, 1.05; N = 13, I2 = 37.9%), hypertensive disorder (RR 0.84, 95% CI 0.66, 1.07; N = 14, I2 = 24.5%), caesarean delivery (RR 1.00, 95% CI 0.95, 1.06; N = 13, I2 = 0.0%), endometritis (RR 1.14, 95% CI 0.41, 3.18; N = 2, I2 = 0.0%) and wound infection or dehiscence (RR 0.55, 95% CI 0.20, 1.48; N = 3, I2 = 56.8%) were similar among pregnant women with GDM managed using either long-acting insulin analogues or NPH (Fig. 2). The gene discussed is INS; the disease is endometritis.