No statistically significant differences were found for risk of admission to neonatal intensive care unit (NICU) (RR 0.97, 95% CI 0.92, 1.03; N = 11, I2 = 0.0%), respiratory distress (RR 0.83, 95% CI 0.64, 1.07; N = 11, I2 = 0.0%), neonatal hypoglycaemia (RR 1.08, 95% CI 0.93, 1.26; N = 14, I2 = 13.3%), 5 min APGAR score < 7 (RR 1.08, 95% CI 0.62, 1.88; N = 8, I2 = 0.0%), neonatal hyperbilirubinemia (RR 0.93, 95% CI 0.77, 1.12; N = 11, I2 = 28.0%), or sepsis (RR 1.28, 95% CI 0.84, 1.95; N = 3, I2 = 0.0%) between babies born to women managed by long-acting insulin analogues or NPH (Fig. 5). This evidence concerns the gene INS and Sepsis.