IL6 and retinal disorder: For example, IL-6 has been implicated in the development of retinopathy of prematurity and other ischemic retinopathies, and use of an oxygen-induced retinopathy model with this Müller-glial-cell-specific Il6ra−/− strain could delineate the specific functions of IL-6 classical and trans-signaling in these retinal diseases58–62.