The most significantly heterogenous variant was an intergenic variant near the HLA-DQB1/DQA2 genes (S3 Fig), where the minor allele (frequency 0.095) decreases natural log TG among those with T2D but yields no difference among those with non-T2D (T2D group: beta = -0.066, p-value = 3.9x10-15; non-T2D group: beta = 0.002, p-value = 0.21; pinteraction = 1.9x10-11). Here, HLA-DQB1 is linked to type 2 diabetes mellitus.