Further, we found that the gene expression levels of DOK2, GBP4, PSMB9, and NLRC5 were changed according to different methylation subclusters, patient state, tumor stage, and clinical T categories; the transcript level of PSMB8 was changed in different methylation subgroups and patients with different survival states (Figures 5(d)––5(e)). The gene discussed is GBP4; the disease is neoplasm.