Four SNPs [Chromosome 3: SNRK and SNRK-AS1-rs202018563G (pvalue = 6.97 × 10−10); Chromosome 13: BRCA2-rs2227943C (pvalue = 4.89 × 10−09); Chromosome 13: ZNF484-rs199826847C (pvalue = 4.91 × 10−09); and Chromosome 11: DCPS-rs1695739G (pvalue = 9.14 × 10−09)] were found to be highly associated significantly (pvalue ≤ 9.14 × 10−09) in patients with breast cancer even after Bonferroni corrections or false discovery rate corrections (corrected α = 0.05/243345 = 2.05 × 10−07) among the exonic variants 24,3345 studied (Figure 1; Table 2). This evidence concerns the gene ZNF484 and breast cancer.