Among them, ITGB3BP, ITGB4, and ITGB6 were up-regulated in BLCA; while ITGA1, ITGA10, ITGA5, ITGA7, ITGA8, ITGA9, ITGB1BP2, and ITGB3 were down-regulated genes; they were defined as DE-ITGs. Here, ITGB6 is linked to bladder transitional cell carcinoma.