Since then, the concept of radiomics has been widely studied in the differentiation of benign and malignant lesions (18), in the preoperative prediction of lymph node metastasis in lung cancer (19), and in the assessment of the mutational status of genes such as Epidermal Growth Factor Receptor (EGFR) (20) and anaplastic lymphoma kinase (ALK) (21). The gene discussed is EGFR; the disease is lung carcinoma.