Serum Hcy was significantly correlated with serum vitamin B12 (r = −0.263, p < 0.001), whereas the correlation with cardiometabolic biomarkers, including blood pressure, BMI, waist circumference, triglycerides, total cholesterol, HDL-C, LDL-C, plasma glucose, HbA1c, C-peptide, insulin resistance, and C-reactive protein, was insignificant or weak. The gene discussed is CRP; the disease is Insulin resistance.