The urine ATF3 at 12 h after surgery was >1216 pg/mL, and its AUC was 0.691 (95% CI 0.576-0.807) with the sensitivity of 0.43 and specificity of 0.85 in the diagnosis of AKI, which was better than that of serum ATF3 and urine ATF3 at other time points. Here, ATF3 is linked to acute kidney injury.