For example, lncAB bound KH-type splicing regulatory protein (KHSRP) and also decreased the expression of KHSRP in papillary thyroid carcinoma, thus increasing CDKN1a (p21) expression and decreasing CDK2 expression to repress cell proliferation (Gou et al., 2018). This evidence concerns the gene CDKN1A and differentiated thyroid carcinoma.