SLC7A11 and neoplasm: Differential analysis of paired 26,772 tumor and normal tissue samples showed that SLC7A11 was upregulated in 17 cancers (BRCA, CESC, CHOL, READ, LUAD, LUSC, PRAD, HNSC, KICH, KIRC, KIRP, LIHC, PAAD, SARC, STAD, COAD and UCEC) but only downregulated in GBM (p < 0.05, Figure 7A).