Moreover, in vivo antitumour effect of Cdk5 gene manipulation by intravenous injection silent 95% genetic expression of Cdk5, which decreased 75.7% tumour weight, 89.6% tumour volume, protein expression profile, and messenger RNA expression, than anti-PD-L1 antibody and PBS control group (Fig. 9g-p). The gene discussed is CDK5; the disease is neoplasm.