TP53 and neoplasm: As a result, p53 losses its function, no or poor DNA binding, and restricted transcription [69,72,73] caused enhancement in tumour-infiltrating lymphocytes in the stroma [73], epithelial-mesenchymal transition, high rate of tumorigenesis, cellular invasion/migration, drug resistance, rapid cell division in TNBC cell lines [74,75], and large-sized tumour growth in females [76].