Technically, in the human genome, anomalies are related to the lncRNA actin fibers associated protein 1 antisense RNA 1 (lncRNA-AFAP1-AS1 or AFAP1-AS1) positioned at the anti-sense chain of AFAP1 gene on chromosome 4, closely associated with breast tumour proliferation and metastasis. This evidence concerns the gene AFAP1 and breast neoplasm.