Independently, another study found that miR-19b-3p mimic significantly increased chondrocyte viability and inhibited apoptosis, it also increased the expression of type II collagen, aggrecan and glycosaminoglycan, and decreased the expression of MMP-1 and MMP-13 caused by IL-1β, suggesting that miR-19b-3p is able to attenuate osteoarthritis injury [10]. This evidence concerns the gene MMP13 and osteoarthritis.