In our previous study, we screened glioma drug resistance-related genes by gene microarray CHIP and identified 21 differentially expressed genes (including six upregulated genes and 15 downregulated genes); they were related to cell growth and differentiation, apoptosis, and signal transduction, respectively [30], among which HDAC2 was most obviously upregulated. This evidence concerns the gene HDAC2 and central nervous system cancer.