The m3C associated genes showed aberrant expression in 17 cancer types for METTL2A (Fig. 1a), 15 cancer types for METTL2B (Fig. 1b), 14 cancer types for METTL6 (Fig. 1c) and 13 cancer types for METTL8 (Fig. 1d). Here, METTL8 is linked to cancer.