ERBB2 and neoplasm: According to the French expert pathologists’ group (GEFPICS) [8] and ASCO [9] guidelines, HER2 score is evaluated by immunohistochemistry (IHC) with score 0 the absence of membrane marking, score 1 + if the marking is between 0 and 2 + , score 2 + a weak to moderate complete membrane staining in > 10% of tumor cells, and score 3 + a complete intense membrane marking in > 10% of cancer cells.