Linear contrast analysis was used to examine the extent to which genes respond differently to HCort, relative to baseline, in PTSD(+) relative to PTSD(–) combat veterans, here termed differential response genes (DRGs); 1,016 and 402 PTSD-specific DRGs were identified in NGN2-neurons following treatment with 100 nM and 1,000 nM HCort, respectively (Fig. 4a and Supplementary Table 6). This evidence concerns the gene NEUROG2 and post-traumatic stress disorder.