In addition, 8-oxo-dG sequencing based on the binding sites of hyperactivated OGG1 (acetylated OGG1 ChIP-Seq) was recently attempted together with sequencing AP sites (AP-Seq), activated APE1 binding sites (APE1 and acetylated APE1 ChIP-Seq; repair-seq), and G-quadruplex sequences (G4 ChIP-Seq using G-quadruplex-specific antibody, BG4) in cancer cell lines (A549 and HCT116)122. The gene discussed is APEX1; the disease is cancer.