In detail, 38% of heterozygous nek978del/+ embryos showed impaired cardiac function, around 68% of heterozygous nek9+/500del embryos developed heart failure and 100% of analyzed compound heterozygous embryos (nek978del/500del) presented with the cardiac phenotype at 72 hpf (Fig. 4E). The gene discussed is NEK9; the disease is heart failure.