GSEA demonstrated enrichment in genes related to CD28 signalling, immunoregulatory interactions between lymphoid and non-lymphoid cells, and other functions in the Sepsisnon-BSI patients, while the SepsisBSI group was characterized by enrichment in genes related to antimicrobial peptides, defensins, G alpha signalling and other pathways (Supplementary Data 4). The gene discussed is CD28; the disease is bathing suit ichthyosis.