METTL3 and acute myeloid leukemia: In addition, the engraftment results (42 days for xenotransplantation and 7 days for homotransplantation) showed that the expression of METTL3, but not METTL3-CD, increased the AML cell proportion in the BM and spleen (Fig. 4C, Supplementary Fig. S7D, G).