METTL3 and acute myeloid leukemia: Flow cytometry showed that METTL3 enhanced the homing of AML cells in the BM and spleen (Fig. 4C and Supplementary Fig. S7G), and immunohistochemistry assays of bone sections indicated that the proportion of METTL3-overexpressing AML cells close to the endosteum was significantly increased (Supplementary Fig. S7C).