ARID4B and B-cell chronic lymphocytic leukemia: Additionally, ASB-CLL was characterized by upregulation of BCAA proteins and downregulation of proteasomal proteins, which is in accordance with the findings observed in the discovery cohort (Supplementary Fig. 8a, b; Wilcoxon signed-rank test p = 0.002 and p < 2.2 × 10−6).