Similarly, pan-cancer analysis of CypB using TCGA data was conducted and CypB transcripts were found to be increased in 20 out of 31 kinds of cancer types, particularly gastrointestinal cancers such as ESCA (Esophageal carcinoma), STAD (Stomach adenocarcinoma), COAD and READ (Supplementary Fig. S1A). This evidence concerns the gene PPIB and carcinoma of esophagus.