Further integrative analysis of Gene Sets Enrichment Analysis (GSEA) showed that CypB expression is positively associated with genes enriched in pathways of cell cycle, ER stress and regulation of Interleukin regulation and β-catenin (Fig. 1F, supplementary Fig S1B–D), which play important roles in the regulation of tumor proliferation and metastasis. Here, PPIB is linked to neoplasm.