The serum profiles of DD-miRNAs over different ages in GRMD dogs (Jeanson-Leh et al, 2014) and DMD patients (Amor et al, 2021) revealed a similar expression pattern to the mCK, of reduced dysregulation level beyond the age of 1 yr in GRMD (Jeanson-Leh et al, 2014) and of 12 yr in DMD (Amor et al, 2021). The gene discussed is CKM; the disease is Duchenne muscular dystrophy.