To define whether these dysregulations are specific to DMD, we quantified DD-miRNAs in serum and muscle biopsies of a collection of mouse models for limb-girdle muscular dystrophies, including LGMDR1 (calpainopathy), LGMDR5 (γ sarcoglycanopathy), and LGMDR3 (α sarcoglycanopathy). This evidence concerns the gene CAPN3 and Duchenne muscular dystrophy.