XRCC3 and central nervous system cancer: We detected a statistically significant association between the XRCC3 p.Thr241Met polymorphism and increased glioma risk when the homozygous model and the recessive model were applied (homozygous, OR = 1.381, 95% CI = 1.081–1.764, P = 0.010; recessive, OR = 1.305, 95% CI = 1.140–1.493, P<0.001).