CD160, CD244, CD274, CSF1R, CTLA4, HAVCR2, IDO1, IL10, KDR, LAG3, LGALS9, PDCD1, PDCD1LG2, TGFB1, TGFBR1, and TIGIT) (Fig 3) and 35 immunostimulators (C10orf54, CD27, CD28, CD40, CD40LG, CD48, CD70, CD80, CD86, CD276, CXCL12, CXCR4, ENTPD1, HHLA2, ICOS, IL2RA, IL6, IL6R, KLRC1, KLRK1, LTA, PVR, TNFRSF4, TNFRSF8, TNFRSF9, TNFRSF13B, TNFRSF13C, TNFRSF14, TNFRSF17, TNFRSF18, TNFRSF25, TNFSF4, TNFSF13, TNFSF13B, and TNFSF14) (Fig 4) that were closely correlated with FABP4 expression in COAD. Here, VSIR is linked to colon adenocarcinoma.