As a cancer suppressor, METTL14 inhibited the progression of colorectal malignancies by modulating the processing of m6A‐dependent primary miR‐37528; m6A modification of circORC5 mediated by METTL14 suppressed the progression of gastric malignancies by regulating the miR‐30c‐2‐3p/AKT1S1 axis29; METTL14 can suppress proliferation and metastasis of colorectal cancer by downregulating oncogenic long non‐coding RNA XIST30; and the metastatic potential of hepatocellular carcinoma was suppressed by METTL14 by modulating the processing of primary microRNA, which is dependent on m6A.31 The gene discussed is METTL14; the disease is hepatocellular carcinoma.