The infection chronification was accompanied by a decrease in the number of peptides that were reactive to all strains (130 to 111), by an increase in the DTU specific reactive peptides for TcI (11 to 34) and TcVI (8 to 22), and by a discrete decrease in the number TcII-specific reactive peptides (18 to 14) (Fig. 5B and C). The gene discussed is TCN2; the disease is infection.